The results in this study also failed to confirm a significant role for DC-SIGN in immature DC-mediated HIV-1 trans infection (Figure 2G), in agreement with previously published studies that have observed at best a two-fold attenuation in immature DC mediated virus capture and trans infection upon virus exposure in the presence of anti-DC-SIGN neutralizing antibodies [12], [13], [54], [55], [56]. The gene discussed is CD209; the disease is infection.