Moreover, the frequency of CD8+ T cells specific for EBV latent, but not lytic, antigens was significantly higher in IFN-β-treated (0.8±0.6%, mean ± SD) than in untreated (0.2±0.2%, mean ± SD ; p = 0.01) active MS patients (Figure 2 B, C). This evidence concerns the gene IFNB1 and myeloid sarcoma.