CD8A and myeloid sarcoma: In contrast, the frequency of lytic antigen-specific CD8+ T cells in active MS patients (1.8±2.8%, mean ± SD) was significantly higher than in HD (0.34±0.28%, mean ± SD; p = 0.03) and tended to be higher than in inactive MS patients (0.3±0.2%, mean ± SD, p = 0.1).