In addition to serine protease HtrA1, which we have recently reported to associate with corneal TGFBIp amyloid in an LCD type 1 variant caused by the V624M mutation in TGFBIp [4], we identified the extracellular serine protease kallikrein-14 (kallikrein-related peptidase 14) [45,46] in the corneal amyloid samples linked to the A546D mutation in TGFBI. Human kallikreins are implicated in normal physiological processes as well as various diseases, including arthritis, cancer, and neurodegenerative diseases. This evidence concerns the gene TGFBI and cancer.