FAS and amyloidosis: The Y571-R588 peptide of TGFBIp has also been found to specifically accumulate in the corneal amyloid in the LCD type 1 variant due to the V624M mutation in TGFBI [4], thus supporting the idea that this region is responsible for amyloidosis in LCDs linked to mutations in the FAS1–4 domain of TGFBIp.