IL1RN and keratoconus: Recently, Kim et al. [39] investigated the association of polymorphisms in IL1A, IL1B, and IL1RN with keratoconus in a Korean population and reported that IL1B promoter polymorphisms rs1143627 (−31 T>C) and rs16944 (−511 C>T) are significantly associated with an increased risk of keratoconus.