Of these, three genes including B7-H4 (8.8-fold induction), S100A7 (6.96-fold induction) and CEACAM6 (5.1-fold induction) were of particular interest since they were previously reported to show limited expression in normal human tissues and over expression in breast tumors, hence potentially useful as breast tumor targets in conjunction with PDEF [25-29]. The gene discussed is VTCN1; the disease is breast neoplasm.