The adiponectin level was negatively correlated with male gender, BMI, hypertension, triglycerides, fasting glucose, 2-h post-OGTT glucose, and HbA1c, and positively correlated with age and HDL cholesterol (all P < 0.05), and was not related to diabetes duration, current smoking, LDL cholesterol (P > 0.05). The gene discussed is ADIPOQ; the disease is diabetes mellitus.