IFNA2 and neoplasm: Statistically, there were significant differences both in tumor volume and weight between the control group and the PEG-IFN-α2b alone group (P<0.0001 vs. control in tumor volume, P<0.0001 vs. control in tumor weight) or the combination group (P<0.0001 vs. control in tumor volume, P<0.001 vs. control in tumor weight) and between the sorafenib alone group and the PEG-IFN-α2b alone group (P<0.005 vs. sorafenib alone in tumor volume, P<0.05 vs. sorafenib alone in tumor weight).