In relation to metabolic and hormonal parameters, although insulin, HOMA index, and leptin were similar between groups, the hypercaloric diet induced hyperglycemia (CD: 90.8 ± 1.4 vs. HD: 97.6 ± 2.4, p = 0.03) and impaired glycemic tolerance (CD: 27198 ± 451 vs. HD: 31867 ± 1463, p = 0.01; Table 1). Here, INS is linked to Hyperglycemia.