Among 25 up-regulated genes in tumours classified into group no. 1, compared to the other two groups, PANTHER software recognized two of them as responsible for chemotherapy resistance (ATP2C1 and ABHD7), two associated with myeloid cells infiltration of tumour mass (SIGLEC10 and SIGLEC11), one related to hypoxia (HYOU1), four genes related to cancer cell motility (MYL6, MYL6B, GPI and ARHGAP), one associated with DNA-repair (XRCC2), one with p53-signalling (RFWD2) and three transcriptional factors (NR6A1, RDH5, CYP19). The gene discussed is SIGLEC10; the disease is cancer.