Recent reports have indicated that hK6 high expression in ovarian cancer [26], colon cancer [16,27], pancreatic cancer [28], non-small cell lung cancer [29] and intracranial tumors [30] could be an independent prognostic factor, suggesting that hK6 may be a prognostic marker for these tumors. The gene discussed is KLK6; the disease is malignant colon neoplasm.