IGHG3 and glioblastoma: We found that the patients with strong linear staining of IgG3 along GBM presented with lower prevalence of gross hematuria (0% vs. 38.5%, P=0.046), higher level of hemoglobin (105.1±25.8 vs. 82.0±24.9 g/L, P=0.038), and lower level of serum creatinine (445.4±333.0 vs. 779.4±367.4 μmol/L, P=0.028), compared with those with weak staining of IgG3.