In the present study, using a longitudinal cohort of patients with Type 2 diabetes, we investigated the association of 16 recently identified eGFR-associated loci (LASS2, GCKR, NAT8, TFDP2, SHROOM3, DAB2, SLC34A1, VEGFA, PRKAG2, ADAM28, PIP5K1B, ATXN2, DACH1, UBE2Q2, UMOD, SLC7A9) with baseline eGFR albuminuria, and time to stage 3B CKD (eGFR<45 ml/min/1.73 m2), in patients with Type 2 diabetes. This evidence concerns the gene PRKAG2 and type 2 diabetes mellitus.