It is interesting that all of the SAMP strains as well as the NOD/ShiLtJ strain share these genes that are involved in DNA repair, i.e., Ogg1 and Mbd4. NOD/ShiLtJ is a mouse model of type 1 diabetes, showing a short life span[27,28]. The gene discussed is MBD4; the disease is type 1 diabetes mellitus.