Although a large number of studies on the relationship between adiponectin −11377CG gene polymorphisms and T2DM have been carried out domestically, the individual studies results were found to be controversial.Ye et al. (2008) observed that adiponectin −11377CG gene polymorphism was associated with the serum adiponectin level, which suggested that this locus polymorphism might increase the T2DM hereditary risk in the Shanxi Chinese population [7]. The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.