PTPRC and acute myeloid leukemia: The bone marrow cellularity of mice transplanted with CD3/CD19-depleted cells was non-significantly reduced compared to control animals (murine and human leukocytes (CD45+): 1.35±0.34×106 cells vs. 1.65±0.17×106 cells), whereas mice receiving non-fractionated AML-MNCs showed a significant reduction in cellularity (1.2±0.24 x106 cells).