Arsenic exposure was associated with decreased expression of the excision repair cross-complementing rodent repair deficiency, complementation group 1 (ERCC1), of the xeroderma pigmentosum group B (XPB) and of the xeroderma pigmentosum group F (XPF) genes in isolated lymphocytes from individuals exposed [59]. The gene discussed is ERCC4; the disease is xeroderma pigmentosum.