SGK1 and hepatocellular carcinoma: This strikingly revealed that there was a group of highly AZD5363-sensitive cell lines with low SGK1 mRNA expression (BT-474, CAMA-1, ZR-75-1, T47D, HCC-1187 and HCC-1569) and a group of resistant cell lines with high SGK1 mRNA expression (HCC-1937, MDA-MB-436, BT-549, MDA-MB-157, MDA-MB-231, HCC-1806 and JIMT-1) (Figure 1A).