There were eight cell lines that displayed intermediate sensitivity towards AZD5363, six having low SGK1 mRNA levels (SUM-52-PE, MDA-MB-453, SK-BR-3, MCF-7, MDA-MB-468 and HCC-1419) and two with elevated SGK1 mRNA levels (BT-20 and HCC-1954) (Figure 1A). Here, SGK1 is linked to hepatocellular carcinoma.