Low p57KIP2 expression has been reported in 89% of non small cell lung cancer [16], 74% of bladder cancer [13], 72% of breast cancer [27], 71% of colorectal carcinoma [23], 60% of ovarian carcinoma [17], 50% of esophageal squamous cell carcinoma [15] and 45% of hepatocellular carcinoma [22], [28]. The gene discussed is CDKN1C; the disease is hepatocellular carcinoma.