The p15INK4b gene has been reported to be homozygously deleted in 50% of T-cell lymphoma [31], 33% of ovarian cancer [19] and 23% of nonsmall cell lung cancer [10], whereas mutations of the p15INK4b gene were detected in 12% of non small cell lung cancer [10]. The gene discussed is CDKN2B; the disease is T-cell non-Hodgkin lymphoma.