Overexpression of c-MET occurs in ∼29% of GBM and directly correlates with poor patient prognosis (Maher et al., 2006; Cancer Genome Atlas Research, 2008; Brennan et al., 2009; Kong et al., 2009; Verhaak et al., 2010; Snuderl et al., 2011; Dunn et al., 2012; Joo et al., 2012). This evidence concerns the gene MET and glioblastoma.