The results of this study were in line with our previous study, which revealed a strong positive correlation between serum levels of sFas and IL-18 in lupus [12–28] and other studies that demonstrated the impressive action of IL-18 [4, 5, 32, 36–38] and sFas [3, 31, 32, 39] in LN. Here, IL18 is linked to systemic lupus erythematosus.