One study in the UK examined the risk association with two intronic SNPs within TCF7L2 (rs7903146 and rs12255372) in individuals of Indian Asian and Afro Carribean origin; in both groups, the risk allele was associated with a higher rate of T2D, but the result did not achieve statistical significance in the Afro Carribean sample [72]. This evidence concerns the gene TCF7L2 and type 2 diabetes mellitus.