Hepatitis histologic scores (Fig. 9A, p<0.05); TFA, S100, and CYP2E1 IgG1 antibody levels; and S100 and CYP2E1 IgG2a antibody levels (Fig. 9B) were lower in IL-6−/− mice than in BALB/cBy mice. This evidence concerns the gene CYP2E1 and Hepatitis.