Mutations in several genes are causative for FALS, including fused in sarcoma/translated in liposarcoma (FUS), superoxide dismutase-1 (SOD1), TAR DNA-binding protein (TARDBP), angiogenin (ANG), vesicle-associated membrane protein B (VAPB), optineurin (OPTN), and valosin-containing protein (VCP) [2], [3]. The gene discussed is SOD1; the disease is liposarcoma.