CD8A and heterotaxy, visceral, 5, autosomal: Experimental depletion of CD8+ T cells in macaques controlling SIV replication lead to a rapid rebound in SIV viremia, whereas the subsequent recovery of the immune system was associated with emergence of SIV-specific CD4+ and CD8+ T cell responses, thus restoring undetectable or low viral loads (Friedrich et al., 2007).