IL1B and Sepsis: In mice with a conditional deletion of Atg7 in the intestinal epithelium, LPS induces higher levels of IL-1β mRNA, compared to wild type controls (Fujishima et al., 2011), while LC3B−/− mice produce higher levels of IL-1β and IL-18 in response to LPS- or cecal ligation and puncture (CLP)-induced sepsis (Nakahira et al., 2011).