A recent study on auto-antigenic SLA/LP peptides targeted by CD4+ T cells, pinpointed residues 452–465 (hereinafter dubbed peptide “A”, sequence NRLDRCLKAVRKER) of the C-terminal, immunodominant region of SLA/LP, as the optimal epitope for CD4+ T cells expressing the AIH disease susceptibility gene HLA-DRB1*03:01[15]. Here, HLA-DRB1 is linked to autoimmune hepatitis.