However, since it is well known that sequence similarity alone is not sufficient for mimicry in autoimmune diseases, we decided to model the interaction of HLA-DRB1*03:01 with peptide “A”, whose interaction has been already proven, and to compare it with a hypothetical complex between HLA-DRB1*03:01 and peptide “B” (Figure 2). This evidence concerns the gene HLA-DRB1 and autoimmune disease.