Specifically, the A/T polymorphism (rs9939609) in the fat mass and obesity associated (FTO) gene (which codes for the protein alpha-ketoglutarate-dependent dioxygenase FTO, also known as fat mass and obesity-associated protein) is a strong candidate to explain how disease modifier polymorphisms may contribute to lower risk for obesity among trained individuals [4]. This evidence concerns the gene FTO and obesity due to melanocortin 4 receptor deficiency.