Leukemia and lymphoma cell lines (Nalm6, Mn60, Jurkat, CEM and KMH2) showed increased p-S6 (2.4 to 8.5-fold) and remarkably elevated p-4EBP1 (63.5 to 77.6-fold) levels by ELISA, compared to normal lymphoid cells (isolated PMNC, T- and B-cells). This evidence concerns the gene EIF4EBP1 and lymphoma.