NFKB1 and systemic lupus erythematosus: In addition, the potency of Ssd in the suppression of NF-κB signaling and its NF-κB-regulated genes expression may be one of the mechanisms against systemic lupus erythematosus [60], pulmonary fibrosis [61], liver inflammation and fibrosis [62], hepatitis B and C [63], viral infection [64], glomerulonephritis [65], and other inflammatory diseases.