On the paternal chromosome, inhibition of CDKN1C is associated with the expression of a long noncoding RNA called KCNQ1OT1 or LIT1 antisense to KCNQ1, the potassium channel gene involved in long-QT-syndrome type 1 and Jervell/Lange-Nielsen syndrome. The gene discussed is KCNQ1OT1; the disease is long QT syndrome 1.