KCNQ1OT1 and Jervell and Lange-Nielsen syndrome: On the paternal chromosome, inhibition of CDKN1C is associated with the expression of a long noncoding RNA called KCNQ1OT1 or LIT1 antisense to KCNQ1, the potassium channel gene involved in long-QT-syndrome type 1 and Jervell/Lange-Nielsen syndrome.