RUNX1 and infection: The Il2ra gene, which encodes the IL-2Rα chain found on activated T cells and is constitutively expressed by Treg cells, was elevated, as were Trp53inp1 (cell cycle progression), Runx1 (Th17 and Treg cells), Ccl3 (secreted by CTL during antiviral responses) and Cxcl2 (expressed by macrophages at sites of infection).