The relative label-free quantification (together with absolute quantification and 2D electrophoresis data) also suggests a possible role of PTM(s) of alpha-2-HS-glycoprotein, a protein related to bone marrow development and function, in MDS patients with refractory anemia and refractory anemia with ringed sideroblasts. The gene discussed is AHSG; the disease is anemia (phenotype).