On the basis of single-factor logistic regression statistical analysis we found that: no statin therapy, leg edema, hepatomegaly, no beta-blocker therapy, renal failure, re-hospitalizations, lower BMI, LVEF, higher NT-proBNP, LVsD, LVdD, MR degree, significantly influenced the risk of death (Table 4). This evidence concerns the gene NPPB and Renal insufficiency.