TNF and familial dilated cardiomyopathy: In conclusion, the pleiotropic effects of atorvastatin in a small dose (10–20 mg/day) significantly reduce levels of inflammatory cytokines (TNF-α, IL-6) and uric acid, as well as improve hemodynamic parameters (LVdD, LVsD and LVEF) in DCM patients after 5 years of treatment, and have a significant impact on the survival of this group of patients.