FOXP3 and hyperinsulinemic hypoglycemia, familial, 4: Interestingly, in contrast to our findings in PG WAT (with the exception of NK cells, which are known to be reduced in T-bet deficiency; Soderquest et al., 2011), the numbers and types of immune cells, including the proportion of Foxp3+ T cells, in the SC WAT depot did not differ between the genotypes.