UCP2 and obesity due to melanocortin 4 receptor deficiency: No significant association between the UCP2 -866G/A polymorphism and the risk of obesity was found using either additive (G allele vs. A allele, REM OR = 0.98, 95% CI: 0.90–1.07), dominant (GG/GA vs. AA, REM OR = 0.94, 95% CI: 0.80-1.10), recessive (GG vs. GA/AA, REM OR = 1.01, 95% CI: 0.90–1.14), or co-dominant (GG vs. AA, REM OR = 0.94, 95% CI: 0.78–1.14) models (Table 4 and Fig. 1).