An IL-4 gene polymorphism has been reported for its association with several diseases such as Graves disease [1], subacute sclerosing panencephalitis [2], rheumatoid arthritis [3-4], end-stage renal disease [5], idiopathic thrombocytopenic purpura [6], chronic polyarthritis [7], fibromyalgia [8), malaria [9], transitional cell carcinoma of the urinary bladder [10], oral cancer [11], and gastric cancer [12,35]. This evidence concerns the gene IL4 and Graves disease.