The transforming growth factor-β (TGF-β) is a key regulator of EMT.24, 25, 26 Furthermore, a critical role in melanoma tumour cell plasticity is covered by the type III TGF-β receptor (TβRIII or betaglycan or endoglin).27 We measured the mRNA and protein levels of TGF-β and TβRIII in FKBP51-depleted or FKBP51-overexpressing SAN melanoma cells. The gene discussed is TGFB1; the disease is melanoma.