PON1 and chronic kidney disease: Serum arylesterase activity in CKD subjects was lower compared with that in non‐CKD control subjects (median [interquartile range] 94 [77 to 112] versus 103 [85 to 121] μmol(L·min) per mL, P<0.001, Figure 1); similarly, PON activity in CKD subjects was lower compared with that in non‐CKD control subjects (median [interquartile range] 474 [275 to 936] versus 586 [301 to 1118] nmol(L·min) per mL, P<0.001, Figure 1).