The intravitreal injection of ranibizumab (IVR), an anti-vascular endothelial growth factor (VEGF) agent, is currently the choice of treatment for subfoveal choroidal neovascularization (CNV) due to age-related macular degeneration (AMD), which is a major cause of irreversible blindness in the elderly in industrialized countries [1,2]. This evidence concerns the gene VEGFA and age-related macular degeneration.