In a study conducted on a small group of resected lung cancer patients, the authors investigated the correlation of SUVmax with the likelihood of lymph node metastasis and reported that, when the SUVmax of the primary tumor was greater than 12, the probability of lymph node metastasis was high, reaching 70%, irrespective of the degree of FDG activity in the lymph node stations [6]. The gene discussed is SMUG1; the disease is metastatic malignant neoplasm in the lymph nodes.