On the above backgrounds of aPS/PT, aPT and aPL antibodies and thrombophilia, hypercoagulability in CD, and increased incidence of SLE and aPL in CD, the presence of aPS/PT, compared with aPL, aPT and anticardiolipin antibodies, were explored in children with CD and their parents, compared with pediatric controls. This evidence concerns the gene F2 and thrombophilia.