CD4 and infection: Indeed, we failed to detect any defects in expression of the TH cell-specific molecules Cd3e and Cd4 in the intestines of infected C2GnT1/2/3−/− mice (Figure 4E), demonstrating that defective TH cell homing to the infected tissue is not likely the cause of the inability to expel worms by day 21 post-infection in the C2GnT1/2/3−/− mice.