RACK1 and hepatocellular carcinoma: The altered RACK1 expression has been identified in several kinds of human diseases, including brain developmental disorders, heart failure, muscle atrophy, breast cancer and pulmonary adenocarcinomas [16], [17], [18], and our previous research also indicates that RACK1 is frequently up-regulated in hepatocellular carcinoma and promotes its chemo-resistance and growth [19].