We thus performed a correlation analysis on the data from 93 prostate tissue samples (46 benign, 30 TMPRSS2:ERG-negative, 17 TMPRSS2:ERG-positive prostate tumors) and found that mRNA levels of ERG and TDRD1 measured by Human Exon 1.0 ST Array are remarkably correlated across all samples (r2 = 0.84), suggesting a mechanistic link between the two genes. The gene discussed is ERG; the disease is prostate neoplasm.