Immunohistochemical analysis of meningiomas showed no significant difference in the expression of components of the VEGF angiogenesis pathway (VEGF, VEGFR2, PDGFR-α, PDGFR-β, neuropilin-1, neuropilin-2, semaphorin 3A, and semaphorin 3F) between sporadic meningiomas and NF2-associated meningiomas. This evidence concerns the gene SEMA3A and meningioma.