AFP and hepatitis A virus infection: Both the peritumoral CD163+ and CD68+ macrophages were associated with the hepatitis-related features, such as serum aspartate aminotransferase (AST) and γ-glutamyl transpeptidase (γ-GT), and the tumor-related features, including serum α-fetoprotein (AFP), tumor size, and presence of microvascular invasion; the density of peritumoral CD68+ macrophages was also associated high TNM stage (Tables 2 and 3).