However, the CXCL12-mediated cell growth and migration are not universal amongst the primary patient-derived GBM cells examined since only two out of four lines (L0 and L1) significantly responded to CXCL12 in terms of cell growth, while only two of the lines (L0 and S2) migrated toward CXCL12. Here, CXCL12 is linked to glioblastoma.