According to a review describing the CASR molecular pathway in colorectal cancer [36], calcium activates certain signalling pathways that participate in cell growth and differentiation via CASR, including the promotion of E-cadherin expression and the suppression of β-catenin and T-cell factor activation, as well as the activation of the p38 mitogen-activated protein kinase cascade [39]. The gene discussed is CASR; the disease is colorectal cancer.