For instance, infection with Mycobacterium bovis BCG induces toll-like receptor 2 (TLR2)-mediated formation of LBs in macrophages [5] while the chemokines eotaxin-1 and RANTES, acting via CCR3 receptors, stimulate LB formation in eosinophils as demonstrated by fluorescence microscopy [43]. Here, CCL5 is linked to infection.