Several studies have suggested a role for TNFAIP3 polymorphisms in the susceptibility to complex autoimmune disorders, including rheumatoid arthritis (RA) [19], [20], psoriasis [21], systemic lupus erythematosus (SLE) [22], [23], Sjögren’s syndrome (SS) [24], Crohn’s disease [24], and ulcerative colitis [25]. Here, TNFAIP3 is linked to systemic lupus erythematosus.