In this study, we focused on the association of five SNPs in TNFAIP3 with VKH disease mainly because they were found to be associated with certain autoimmune or rheumatic disease, including psoriasis [21], [32], SLE, RA [20], [23], [33], juvenile idiopathic arthritis [34] and psoriatic arthritis [35]. This evidence concerns the gene TNFAIP3 and systemic lupus erythematosus.